See his photograph at the website of the Massachusetts Historical Society.
- Anna Blagden, born about July 1832
- John P. Blagden, born 6 August 1833
- George Blagden, born about April 1835; married Frances Meredith Dexter; died 1 January 1905
- Edward Reynolds Blagden, born 10 February 1837 at Cambridge, Massachusetts; married Katherine Peabody Converse; died 9 August 1894 at Cambridge, Massachusetts
- Thomas Blagden, born 28 October 1838 at Boston, Massachusetts; m. Sarah E. Sampson; died 5 November 1892 at New York, New York
- Samuel Phillips Blagden, born 3 October 1840 at Boston, Massachusetts; married 1) Annie Christine White; 2) Julia Goodman Clark; died 1906 at New York, New York
- Sally Phillips Blagden, born 14 August 1842; m. Edward C. Sampson. She is the daughter at whose home Rev. Blagden spent his final years.
- Miriam Blagden, born November 1845; died 1849